THC, CBD, cannabinoids, litlamorao tsa psychoactive - mohlomong u utloile bonyane mantsoe ana a 'maloa haeba u ntse u leka ho utloisisa THC, CBD le liphapang lipakeng tsa tsona.Mohlomong o kile oa kopana le sistimi ea endocannabinoid, li-cannabinoid receptors, esita le terpenes.Empa ha e le hantle ke eng?
Haeba u batla mokhoa oa ho utloisisa hore na ke hobane'ng ha lihlahisoa tsa THC li etsa hore u phahame, 'me lihlahisoa tsa CBD ha li u etse le hore na li amana joang le li-endocannabinoids, rea u amohela, u sebakeng se nepahetseng.
Li-cannabinoids le karolo ea ECS
Ho utloisisa THC vs CBD le hore na li re ama joang, u lokela ho qala ka ho utloisisa tsamaiso ea endocannabinoid (ECS), e thusang 'mele ho boloka botsitso ba ts'ebetso ka likarolo tsa eona tse tharo tse kholo: "lenģosa" limolek'hule, kapa li-endocannabinoids, tseo 'mele ea rona e li hlahisang;li-receptors limolek'hule tsena li tlama ho;le li-enzyme tse li senyang.
Bohloko, khatello ea maikutlo, takatso ea lijo, metabolism ea matla, ts'ebetso ea pelo, moputso le tšusumetso, ho ikatisa le ho robala ke tse ling tsa mesebetsi ea 'mele e amang cannabinoids ka ho sebetsa ho ECS.Melemo e ka bang teng ea bophelo bo botle cannabinoids e mengata 'me e kenyelletsa phokotso ea ho ruruha le taolo ea ho nyekeloa ke pelo.
Seo THC e se etsang
Cannabinoid e ngata ka ho fetisisa le e tsebahalang haholo e fumanehang semeleng sa cannabis ke tetrahydrocannabinol (THC).E kenya tšebetsong receptor ea CB1, karolo ea ECS bokong e laolang botahoa.Botahoa ba THC bo bontšitsoe ho eketsa phallo ea mali ho prefrontal cortex, sebaka sa boko se ikarabellang bakeng sa ho etsa liqeto, tlhokomelo, tsebo ea likoloi, le mesebetsi e meng ea tsamaiso.Sebopeho se nepahetseng sa litlamorao tsa THC mesebetsing ena e fapana ho ea ka motho.
Ha THC e tlamella ho li-receptor tsa CB1, e boetse e baka maikutlo a thabo ho tsoa tsamaisong ea moputso oa boko.Cannabis e kenya tšebetsong tsela ea moputso oa boko, e etsang hore re ikutloe re le monate, 'me e eketsa menyetla ea rona ea ho ja hape nakong e tlang.Kameho ea THC tsamaisong ea meputso ea boko ke ntlha e kholo ea bokhoni ba cannabis ho hlahisa maikutlo a botahoa le thabo.
Seo CBD e se etsang
THC ha se eona feela motsoako oa cannabis o nang le phello e tobileng ts'ebetsong ea boko.Papiso e hlokomelehang haholo ke cannabidiol (CBD), e leng cannabinoid ea bobeli e fumanehang semeleng sa cannabis.Hangata CBD e nkoa e se psychoactive empa sena sea khelosa kaha ntho efe kapa efe e nang le phello e tobileng ts'ebetsong ea boko ke psychoactive.CBD ehlile e baka litlamorao tsa psychoactive ha e sebelisana le boko le tsamaiso ea methapo e bohareng, kaha ho tlalehoa e na le thepa e matla ea ho thibela ho oela le ho thibela matšoenyeho.
Kahoo le ha CBD e hlile e le psychoactive, ha e noe.Ke hore, ha e u phahamisetse holimo.Ke hobane CBD e mpe haholo ho kenya tšebetsong CB1 receptor.Ebile, bopaki bo fana ka maikutlo a hore e hlile e kena-kenana le ts'ebetso ea receptor ea CB1, haholo boteng ba THC.Ha THC le CBD li sebetsa 'moho ho ama ts'ebetso ea li-receptor tsa CB1, basebelisi ba ikutloa ba le bobebe haholoanyane, ba na le monyetla o tlase oa ho ba le paranoia ha ba bapisoa le litlamorao tse utluoang ha CBD e le sieo.Ke hobane THC e kenya tšebetsong receptor ea CB1, ha CBD e e thibela.
CBD le THC li sebelisana joang
Ka mantsoe a bonolo feela, CBD e ka sireletsa khahlanong le ho senyeha ha kelello ho amanang le ho pepesehela ho feteletseng ho THC.Phuputso ea 2013 e phatlalalitsoeng ho Journal of Psychopharmacology e ile ea fana ka THC ho barupeluoa mme ea fumana hore ba neng ba fuoe CBD pele ho tsamaiso ea THC ba ne ba bontša ho fokola ha mohopolo ho feta bakuli ba fuoeng placebo - ho bontša hape hore CBD e ka thibela kelello ea THC. likhaello.
Ebile, tlhahlobo ea 2013 ea lithuto tse ka bang 1,300 tse phatlalalitsoeng likoranteng tsa mahlale li fumane hore "CBD e ka thibela litlamorao tse mpe tsa THC."Tlhahlobo e boetse e supa tlhoko ea lipatlisiso tse ling le ho sheba litlamorao tsa CBD ts'ebelisong ea THC maemong a nnete a lefats'e.Empa lintlha tse teng li hlakile hore CBD hangata e khothaletsoa e le pheko bakeng sa ba sebelisitseng THC e ngata ka boomo mme ba iphumana ba imetsoe.
Li-cannabinoids li sebelisana le litsamaiso tse ngata 'meleng
THC le CBD li tlamella lipheo tse ling tse 'maloa' meleng.Ka mohlala, CBD e na le bonyane libaka tse 12 tsa liketso bokong.Mme moo CBD e ka lekanyang litlamorao tsa THC ka ho thibela li-receptor tsa CB1, e kanna ea ba le litlamorao tse ling ho metabolism ea THC libakeng tse fapaneng tsa ts'ebetso.
Ka lebaka leo, CBD e kanna ea se ke ea thibela kapa ea leka-lekanya litlamorao tsa THC kamehla.E kanna ea ntlafatsa ka kotloloho melemo ea bongaka e ka bang teng ea THC.Ka mohlala, CBD e ka ntlafatsa phomolo ea bohloko e bakoang ke THC.THC e kanna ea ba anti-inflammatory le neuroprotective antioxidant, haholo ka lebaka la ts'ebetso ea eona ea li-receptor tsa CB1 sebakeng sa taolo ea bohloko bokong.
Phuputso e tsoang ho 2012 e senotse hore CBD e sebelisana le li-receptor tsa alpha-3 (α3) glycine, sepheo sa bohlokoa bakeng sa ho sebetsana le bohloko ba mokokotlo, ho thibela bohloko bo sa foleng le ho ruruha.Ke mohlala oa seo ho thoeng ke phello e khothatsang, moo metsoako e fapaneng ea cannabis e sebetsang hammoho ka kakaretso ho hlahisa phello e kholo ho feta ha e sebelisoa ka thoko.
Empa le tšebelisano ena ha e hlake ka ho felletseng.Phuputsong ea Pherekhong 2019, bafuputsi ba fumane hore litekanyetso tse tlase tsa CBD li hlile li ntlafalitse litlamorao tse tahang tsa THC, athe litekanyetso tse phahameng tsa CBD li fokotsa litlamorao tse tahang tsa THC.
Terpenes le phello e khothatsang
Hoa khoneha hore litla-morao tse ling tse tsebahalang haholo tsa cannabis (joalo ka bethe-lock) li ka ba le kamano e fokolang haholo le THC ka boeona, empa ho fapana le hoo, tlatsetso e amanang le limolek'hule tse sa tsejoeng haholo.Lik'hemik'hale tse bitsoang terpenes li fa limela tsa cannabis litatso le monko oa tsona o ikhethang.Li fumaneha limela tse ngata - joalo ka lavender, makhapetla a lifate le hop - 'me li fana ka monko oa oli ea bohlokoa.Terpenes, e leng sehlopha se seholo ka ho fetisisa sa li-phytochemicals tse tsejoang ka har'a cannabis, le tsona li ipakile e le karolo ea bohlokoa ea phello ea moeti.Ha se feela hore terpenes e fa cannabis tatso le monko o ikhethang, empa hape e bonahala e ts'ehetsa limolek'hule tse ling tsa cannabis ho hlahisa litlamorao tsa 'mele le boko.
Boemo bo tlase
Cannabis ke semela se rarahaneng se nang le lipatlisiso tse fokolang tse fumanehang mabapi le litlamorao tsa sona le litšebelisano le 'mele oa motho - mme re sa tsoa qala ho ithuta mekhoa e mengata ea THC, CBD le metsoako e meng ea cannabis e sebetsang hammoho le ho sebelisana le ECS ea rona ho fetola tsela eo re ikutloang ka eona.
Nako ea poso: Oct-19-2021